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. 2023 Sep 26;14(9):636. doi: 10.1038/s41419-023-06053-y

Fig. 5. YAP1 regulated PD-L1 expression in small cell lung cancer (SCLC).

Fig. 5

A mRNA expression level of PD-L1 in different SCLC cell lines. B, C MFI of PD-L1 in different SCCL cell lines. D, F Microscopy of SHP77, H446, and H526 cell lines with stable overexpression of YAP1. Histograms depicted MFI of nuclear-localized YAP1 in SCLC-OE and NC cells. G Gating strategy of SCLC cells with stable overexpression of YAP1. H MFI of PD-L1 in OE and NC cells. I MFI of nuclear-localized YAP1 and PD-L1 in SCLC-Y cells after verteporfin exposure. MFI median fluorescence intensity, NC negative control, OE overexpression, PD-L1 program death-ligand 1, YAP1 yes-associated protein 1.