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. 2023 Sep 26;14(9):636. doi: 10.1038/s41419-023-06053-y

Fig. 6. YAP1 modulated immune cell abundances, apoptosis, and functions in SCLC.

Fig. 6

A Gating strategy of different immune cells. B The proportions of different immune cells in the SCLC-Y group (DMS114 and H2286) and the SCLC-A/N/P group (SHP77, H446, and H526). C MFI of Fas in CD45+ immune cells and CD45 + CD3 + T cells in five coculture groups (tumor cells and PBMCs). D MFI of Ki67 in different immune cells in two coculture systems of SCLC-Y cells and PBMCs after verteporfin exposure. E MFI of Fas in CD45+ immune cells and CD45 + CD3 + T cells in two SCLC-Y and PBMCs coculture systems after verteporfin exposure. F The proportions of Granzyme-B+ immune cells and activated T cells (CD45 + CD3 + HLA-DR + ) in two coculture systems of SCLC-Y cells and PBMCs after verteporfin exposure. SCLC small cell lung cancer, MFI median fluorescence intensity, PBMCs peripheral blood mononuclear cells.