Table 3.
Adjusted odds ratios (95% CI) summarising the multivariable association of covariates with presence of sarcopenia at four time points.
| Covariate | Baseline | Year 1∗ | Year 2 | Year 3 |
|---|---|---|---|---|
| Older age | 1.43 (1.09–1.93) | 1.32 (0.92–1.93) | 1.06 (0.67–1.68) | 1.62 (0.95–2.98) |
| MELD at LT | 0.96 (0.93–0.98) | |||
| DM pre-LT | 0.77 (0.31–1.75) | 0.73 (0.36–1.47) | 0.71 (0.32–1.56) | 0.31 (0.11–0.79) |
| CKD pre-LT | 0.24 (0.04–0.87) | 2.26 (0.61–9.66) | 1.37 (0.32–6.05) | |
| Male sex | 2.94 (1.71–5.23) | 2.11 (1.06–4.30) | 0.84 (0.36–2.00) | 0.98 (0.35–2.74) |
| Higher BMI | 1.00 (0.95–1.06) | 0.98 (0.91–1.05) | ||
| Any rehab within 90 days from LT | 2.02 (0.99–4.20) | 1.23 (0.55–2.76) | ||
| Tacrolimus Exposure | 0.93 (0.72–1.19) | 0.99 (0.74–1.33) | ||
| Baseline sarcopenia | 8.47 (3.80–20.70) | 5.78 (2.43–14.80) | 11.47 (4.01–37.91) |
The text in bold is statistically significant.
Year 1 scan done 180–-365 days after LT. CKD, chronic kidney disease; DM, diabetes mellitus; LT, liver transplant; MELD, model for end-stage liver disease.