Table 4.

Univariate and multivariate logistic regression analysis of factors potentially associated with the presence of OVs in patients with PSC with an UGIE within 12 months.

	Univariate			Multivariate
	OR	95% CI	p value	OR	95% CI	p value
Male sex	2.308	0.492–10.818	0.289
Age, years	0.976	0.932–1.022	0.297
PSC Mayo RS	3.672	1.694–7.962	0.001	1.339	0.332–5.404	0.682
Child-Pugh score	3.868	1.780–8.402	0.001	1.660	0.373–7.393	0.506
MELD score	1.634	1.215–2.198	0.001	1.396	0.641–3.039	0.401
Spleen LD, cm	1.264	1.040–1.535	0.018	1.180	0.735–1.894	0.493
Total bilirubin, mg/dl	1.901	1.185–3.048	0.008	1.026	0.946–1.114	0.536
ALT (IU/L)	1.004	0.944–1.013	0.468
AST (IU/L)	1.012	0.999–1.025	0.063
ALP (IU/L)	0.999	0.996–1.001	0.412
Platelets/mmc	0.994	0.988–1.000	0.043	0.996	0.987–1.005	0.369
Albumin g/dl	0.090	0.020–0.397	0.001	0.889	0.601–1.314	0.555
F-TE LSM, kPa	1.075	1.032–1.121	0.001	0.997	0.937–1.060	0.920
ElastPQ LSM, kPa	1.073	1.024–1.124	0.003	0.916	0.813–1.032	0.149
ElastPQ SSM, kPa	1.123	1.037–1.216	0.004	1.137	1.020–1.268	0.021
LSPS	1.741	1.199–2.527	0.004	1.606	0.974–2.648	0.063

Binary logistic regression analysis used; p value ≤0.05 represents the significance level.

ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; F-TE, liver elastography performed with FibroScan; LD, longitudinal diameter; LSM, liver stiffness measurement; LSPS, liver stiffness x spleen diameter-to-platelet ratio score; MELD, model of end-stage liver disease; OR, odds ratio; OVs, oesophageal varices; PSC, primary sclerosing cholangitis; RS, risk score; SSM, spleen stiffness measurement; UGIE, upper gastro-intestinal endoscopy.