Table 1.
Total and Individual Intrahepatic Bile Acid Levels
| pmol/mg liver | Mdr2-/- Ctrl | Mdr2-/- GLP-2 |
|---|---|---|
| ToMCA | 23.9 ± 4.2 | 81.93 ± 52.2 |
| TαMCA | 5.5 ± 1.4 | 4.2 ± 2.4 |
| TβMCA | 67.2 ± 21.3 | 158.4 ± 21.3a |
| TCA | 106.0 ± 15.3 | 211.3 ± 108.9 |
| TUDCA | 1.0 ± 0.2 | 1.1 ± 0.6 |
| TCDCA | 5.5 ± 0.59 | 8.5 ± 3.2 |
| TDCA | 1.7 ± 0.4 | 1.4 ± 1.0 |
| oMCA | 5.4 ± 2.2 | 16.4 ± 4.76a |
| αMCA | 1.3 ± 0.9 | 1.8 ± 1.0 |
| βMCA | 19.3 ± 5.2 | 47.5 ± 12.0a |
| Total | 240.1 ± 27.8 | 527.5 ± 312.6 |
αMCA, alpha muricholic acid; βMCA, beta muricholic acid; oMCA, omega muricholic acid; TCA, taurocholic acid; TCDCA, taurochenodeoxycholic acid; TDCA, taurodeoxycholic acid; TαMCA, tauro-alpha muricholic acid; TβMCA, tauro-beta muricholic acid; ToMCA, tauro-omega muricholic acid; TUDCA, tauroursodeoxycholic acid.
a
Significantly different from Mdr2-/- Ctrl. P ≤ .05 was considered significant.