Table 1.
Antimicrobial activity of compounds shown in Fig. 2 against various bacterial strains. — indicates that activity was not tested.
| MIC (µg/mL) |
Hemolytic data HC50 (µg/mL) |
Selectivity of MRSA: HC50/ MICMRSA (µg/mL) |
|
|---|---|---|---|
| Compound | Gram + | ||
| C 8 -K-cBB 1 | > 25 | — | — |
| C 10 -K-cBB 1 | > 25 | — | — |
| C 12 -K-cBB 1 | 5 | — | — |
| C 14 -K-cBB 1 | 5 | — | — |
| C 16 -K-cBB 1 | 1 | 62.5 | 62.5 |
| C 16 -K-cBB 2 | 10 | — | — |
| C 16 -K-cBB 3 | > 25 | — | — |
| C 16 -K-bBB 1 | 2 | — | — |
| C 16 -K-bBB 2 | 5 | — | — |
| C 16 -K-bBB 3 | > 25 | — | — |
| C 16 -K-hBB 1 | 5 | — | — |
| C 16 -K-hBB 2 | 2 | — | — |
| C 16 -K-hBB 3 | 10 | — | — |