Table 1.
Distribution of CART immunoreactivity patterns in the C boutons synapse in different ages | |||||
---|---|---|---|---|---|
Age groups | |||||
Patterns | P10 | P25 | 8 to 9 wk | 6 mo | 1 y old |
Compact | 7.2% | 9.3% | 6.8% | 7.8% | 14.7% |
Puncta along the synapse | 15.4% | 16.7% | 23.1% | 29.4% | 24.1% |
1–3 puncta | 31.6% | 30.9% | 27.6% | 26.4% | 27.2% |
Peripheral puncta | 19.2% | 12.5% | 11.7% | 18.4% | 19.6% |
No CART | 26.6% | 30.6% | 30.8% | 18% | 14.4% |
In the P10, P25, 8 to 9 wk, 6 mo old, 1-y-old age groups (n = 3 mice per age group), a mean of 544 synapses per motor neuron (1,208 μm optical section thickness) were evaluated in lumbar segments (14 μm slices). The percentage of CART+ C bouton synapses differs depending on age.