TABLE 1.

Tumor responses based on RECIST 1.1.

Response	All patients (n = 184)	First‐line patients (n = 119)	Later line patients (n = 65)	p value
Objective response rate	55 (29.9%)	45 (37.8%)	10 (15.4%)	0.0020
Disease control rate	131 (71.2%)	99 (83.2%)	32 (49.2%)	<0.001
Complete response	4 (2.2%)	3 (2.5%)	1 (1.5%)	NS
Partial response	51 (27.7%)	42 (35.3%)	9 (13.8%)	<0.001
Stable disease	76 (41.3%)	54 (45.4%)	22 (33.8%)	<0.001
Progressive disease	53 (28.8%)	20 (16.8%)	33 (50.8%)	NS

Abbreviation: NS, not significant.