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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2023 Apr 12;15(4):e1889. doi: 10.1002/wnan.1889

Table 1:

Select fibrous and hydrogel-based nanomaterials employed as wound dressings in surgery.

Composition Architecture Mode of Administration Animal Model, Wound Type Skin Wound Closure (control vs. test) Refs.
Poly(lactic-co-glycolic acid) and poly(ethylene glycol) Fiber Blowspinning Pig, partial thickness 100% vs. 80% (t=7d) (Daristotle, Lau, et al., 2020)
Poly(lactide-co-caprolactone) Fiber Blowspinning Pig, partial thickness 100% vs. 80% (t=7d) (Daristotle et al., 2021)
Chitosan-poly(vinyl alcohol)-zinc oxide Fiber Electrospinning Rabbit, full thickness 38% vs. 100% (t=12d) (Ahmed et al., 2018)
L-nitroarginine polyester amide with Pluronic F127 and Tegaderm Hydrogel Prefabricated Rat, full thickness 40% vs. 80% (t=7d) (M. He et al., 2019)
Chitosan loaded with rose bengal, poly(pyrrole), poly(vinyl alcohol) Hydrogel Prefabricated Rat, partial thickness 15% vs. 40% (t=8d) (J. Wang et al., 2021)
Poly(vinyl alcohol)/glycerol loaded with curcumin Hydrogel Injection Mouse, full thickness 20% vs. 70% (t=5d) (Wu et al., 2023)
Gelatin/dopamine Hydrogel Injection Mouse, full thickness 40% vs. 80% (t=7d) (Y. Huang et al., 2020)
Poly(dopamine)–poly(acrylamide) Hydrogel Prefabricated Mouse, full thickness 10% vs. 50% (t=5d) (Han, Yan, et al., 2017)