Table 1.
Estimated semisolid MTC parameters, free bulk water T1 relaxation time, MTC at ±3.5 ppm, APT#, and rNOE# signal intensities (mean ± standard deviation and 95% confidence interval) obtained from Recon-RNN for white matter and gray matter of eight healthy volunteer human brain. Note that the Recon-RNN was trained with a forty million dataset synthesized from the RNN-based deep Bloch simulator (deepBS-RNN). Mean and standard deviations values were obtained across subjects.
| ROIs | kmw (Hz) | F (%) | T2m (μs) | T1w (s) | B1 = 1 μT | B1 = 1.5 μT | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| MTC (%) |
APT# (%) |
rNOE# (%) | MTC (%) |
APT# (%) |
rNOE# (%) | ||||||
| WM | Mean ± STD | 14.6 ± 0.9 | 17.0 ± 0.6 | 14.6 ± 0.5 | 1.1 ± 0.1 | 35.6 ± 0.4 | 9.5 ± 0.5 | 11.7 ± 0.5 | 51.8 ± 0.5 | 9.0 ± 0.7 | 9.3 ± 0.6 |
| 95% CI | 14.1 – 15.1 | 16.7 – 17.3 | 14.4 – 14.9 | 1.1 – 1.2 | 35.4 – 35.8 | 9.2 – 9.8 | 11.4 – 12.0 | 51.5 – 52.0 | 8.6 – 9.4 | 8.9 – 9.6 | |
| GM | Mean ± STD | 19.8 ± 3.0 | 12.1 ± 1.3 | 14.9 ± 0.6 | 1.3 ± 0.1 | 32.9 ± 0.9 | 7.3 ± 0.9 | 9.3 ± 0.9 | 49.5 ± 1.2 | 6.1 ± 1.0 | 6.3 ± 1.1 |
| 95% CI | 18.2 – 21.5 | 11.4 – 12.9 | 14.5 – 15.2 | 1.2 – 1.4 | 32.4 – 33.4 | 6.9 – 7.8 | 8.8 – 9.7 | 48.8 – 50.1 | 5.6 – 6.6 | 5.7 – 6.9 | |
| p -value | < 0.01 | < 0.01 | 0.24 | < 0.01 | < 0.01 | < 0.01 | < 0.01 | < 0.01 | < 0.01 | < 0.01 | |