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Sample demographics.
| GWAS or proxy-LOAD cases | GWAS controls | Brain tissue evidence | ROSMAP single cell cases | ROSMAP single cell controls | Morabito single cell cases | Morabito single cell controls | |
|---|---|---|---|---|---|---|---|
| N | 111,326 | 677,663 | 9 | 24 | 24 | 12 | 8 |
| Age mean (SD) | 76.8 (6.6) | 67.6 (10.9) | 77.7 (3.5) | 85.7 (4.2) | 85.6 (4.3) | 87.7 (3.6) | 81.6 (5.7) |
| Age of AD onset mean (SD) | 78.1 (4.8) | - | - | - | - | - | - |
| females % | 63 | 54 | 33 | 50 | 50 | 50 | 38 |
| APOE e4 allele frequency % | 30 | 14 | - | 32 | 14 | 33 | 0 |
