Figure 4.
Univariate analysis of TFR during the 5-year study period
Based on Cox proportional hazards model with EFS as dependent variable and sex, age group, duration of prior dasatinib, duration of prior TKI, prior therapy line and Sokal score as predictor variables. Hazard ratios are estimated for male over female, age < 65 over age ≥ 65 years, duration of prior dasatinib ≥ median over < median, duration of prior TKI ≥ median over < median, first line of therapy over 2nd-/3rd-line of therapy, Sokal score of intermediate over low and Sokal score of high over intermediate.
Numbers of patients (n) for each covariate are based on non-missing information.
Abbreviations: CI, confidence interval; EFS, event-free survival; TFR, treatment-free remission; TKI, tyrosine kinase inhibitor.