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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: J Thorac Oncol. 2023 May 18;18(9):1222–1232. doi: 10.1016/j.jtho.2023.05.008

Figure 1. Differential gene expression in tumors of patients with SCLC enrolled on CheckMate 032.

Figure 1.

Heat-map of gene expression in the 286 SCLC tumors analyzed, arrayed horizontally and sorted by relative expression of ASCL1, NEUROD1, POU2F3, and YAP1, defining subtype assignments to categories SCLC-A, -N, -P, and -Y. Additional genes shown include INSM1, upregulated in the neuroendocrine-high subtypes SCLC-A and -N, and MYC, most highly expressed in SCLC-P.