Table 3:
Unweighted and inverse probability of participation-weighted measures of non-motor symptom prevalence and quality of life in the Fox Insight study
| Unweighted | Weighted | Difference between weighted and unweighted | |
|---|---|---|---|
| NMS Quest, mean (95% CI), n=21978 | 11.7 (11.6, 11.8) | 13.7 (13.5, 13.9) | 2.0 (1.8, 2.2) |
| Drooling, % (95% CI), n=21978 | 38.6 (37.9, 39.2) | 54.4 (52.9, 55.9) | 15.8 (14.1, 17.4) |
| Hyposmia, % (95% CI), n=21976 | 29.9 (29.3, 30.5) | 36.9 (35.6, 38.5) | 7.0 (5.4, 8.5) |
| Dysphagia, % (95% CI), n=21974 | 38.7 (38.1, 39.4) | 49.2 (47.8, 50.8) | 10.5 (8.9, 12.1) |
| Nausea/vomiting, % (95% CI), n=21974 | 23.3 (22.8, 23.9) | 24.4 (23.2, 25.7) | 1.1 (−0.3, 2.5) |
| Constipation, % (95% CI), n=21972 | 59.3 (58.6, 59.9) | 62.5 (61.0, 64.0) | 3.2 (1.7, 4.8) |
| Bowel incontinence, % (95% CI), n=21970 | 17.1 (16.6, 17.6) | 28.4 (27.0, 29.9) | 11.3 (9.7, 12.8) |
| Incomplete bowel emptying, % (95% CI), n=21967 | 51.1 (50.4, 51.7) | 53.4 (51.9, 54.9) | 2.3 (0.7, 4.0) |
| Urinary urgency, % (95% CI), n=21965 | 71.1 (70.5, 71.7) | 76.0 (74.8, 77.4) | 4.9 (3.6, 6.2) |
| Nocturia, % (95% CI), n=21963 | 73.9 (73.3, 74.5) | 77.2 (76.0, 78.4) | 3.3 (1.9, 4.6) |
| Pain, % (95% CI), n=21963 | 40.5 (39.8, 41.1) | 42.1 (40.7, 43.5) | 1.6 (0.1, 3.2) |
| Weight change, % (95% CI), n=21963 | 14.6 (14.1, 15.1) | 20.4 (19.1, 21.8) | 5.8 (4.6, 7.1) |
| Forgetfulness, % (95% CI), n=21961 | 56.0 (55.4, 56.7) | 66.0 (64.6, 67.4) | 10.0 (8.5, 11.4) |
| Loss of interest, % (95% CI), n=21960 | 43.5 (42.8, 44.1) | 53.7 (52.2, 55.1) | 10.2 (8.5, 11.7) |
| Hallucinations, % (95% CI), n=21960 | 16.3 (15.8, 16.8) | 28.4 (27.0, 30.0) | 12.1 (10.5, 13.7) |
| Difficulty concentrating, % (95% CI), n=21958, | 54.3 (53.6, 54.9) | 63.0 (61.5, 64.4) | 8.7 (7.2, 10.4) |
| Depression, % (95% CI), n=21957 | 59.7 (59.1, 60.4) | 64.2 (62.8, 65.7) | 4.5 (2.9, 6.0) |
| Anxiety, % (95% CI), n=21954 | 42.7 (42.0, 43.3) | 45.8 (44.4, 47.3) | 3.1 (1.5, 4.8) |
| Altered interest in sex, % (95% CI), n=21952 | 37.7 (37.1, 38.4) | 41.0 (39.6, 42.6) | 3.3 (1.7, 4.9) |
| Difficulty with sex, % (95% CI), n=21950 | 36.9 (36.2, 37.5) | 44.2 (42.8, 45.7) | 7.3 (5.8, 8.9) |
| Dizziness, % (95% CI), n=21948 | 51.1 (50.5, 51.8) | 61.1 (59.6, 62.5) | 10.0 (8.3, 11.5) |
| Fall, % (95% CI), n=21947 | 27.1 (26.6, 27.7) | 40.2 (38.8, 41.8) | 13.1 (11.4, 14.6) |
| Difficulty staying awake, % (95% CI), n=21947 | 23.1 (22.6, 23.7) | 31.7 (30.1, 33.2) | 8.6 (7.0, 10.1) |
| Difficulty falling/staying asleep, % (95% CI), n=21946 | 65.2 (64.6, 65.8) | 64.5 (63.0, 65.9) | −0.7 (−2.2, 0.9) |
| Vivid dreams, % (95% CI), n=21945 | 36.9 (36.3, 37.6) | 40.1 (38.5, 41.5) | 3.2 (1.5, 4.7) |
| Dream enactment, % (95% CI), n=21945 | 37.0 (36.4, 37.6) | 41.0 (39.7, 42.4) | 4.0 (2.5, 5.5) |
| Restless legs, % (95% CI), n=21945 | 50.5 (49.9, 51.2) | 56.9 (55.5, 58.3) | 6.4 (4.8, 7.8) |
| Leg edema, % (95% CI), n=21944 | 23.4 (22.8, 23.9) | 34.4 (33.0, 35.8) | 11.0 (9.4, 12.5) |
| Excessive sweating, % (95% CI), n=21943 | 24.6 (24.1, 25.2) | 24.9 (23.5, 26.2) | 0.3 (−1.2, 1.7) |
| Double vision, % (95% CI), n=21941 | 22.4 (21.9, 23.0) | 30.1 (28.7, 31.6) | 7.7 (6.3, 9.1) |
| Delusions, % (95% CI), n=21940 | 5.7 (5.4, 6.0) | 14.3 (13.2, 15.6) | 8.6 (7.4, 9.9) |
| PDAQ-15, mean (95% CI), n=21485 | 47.9 (47.7, 48.1) | 40.7 (40.2, 41.2) | −7.2 (−7.7, −6.6) |
| PDQ-8, mean (95% CI), n=22240 | 26.5 (26.2, 26.7) | 37.1 (36.5, 37.8) | 10.6 (10.0, 11.3) |