Table 2.

List of upregulated (+) and downregulated (−) genes in common among the two ovulation data sets and the intracranial aneurysms (ICA) data set.

Gene	Gene function	Ovulation (Liu et al., 2017) Log2FC	Ovulation (Liu et al., 2017) P-value	Ovulation (Park et al., 2020) Log2FC	Ovulation (Park et al., 2020) P-value	ICA (Kurki et al., 2011) Log2FC	ICA (Kurki et al., 2011) P-value
Sat1	N1-acetyltransferase	1.093	0.01	0.330	<0.0001	2.539	0.0002
Glul	Ligase	4.073	<0.0001	0.989	<0.0001	2.296	0.0003
Ucp2	Mitochondrial protein	3.170	<0.0001	0.940	<0.0001	2.195	0.01
Rgs2	GPCR regulator	7.205	<0.0001	0.821	<0.0001	1.922	0.01
Angptl4	Secreted protein	1.792	<0.0001	0.317	<0.0001	1.811	0.002
Abca1	ATP binding	3.389	<0.0001	0.312	<0.0001	1.736	0.007
Baz1a	Chromatin assembly	1.390	0.002	0.656	<0.0001	1.269	0.008
Ddx3x	Helicase	1.603	<0.0001	0.334	<0.0001	0.824	0.0007
Nfkbia	NFKB inhibitor	2.861	<0.0001	0.450	<0.0001	0.799	0.04
Pfkfb4	Kinase	2.596	<0.0001	0.447	<0.0001	0.705	0.04
Adam8	Metalloproteinase	3.550	<0.0001	0.811	0.03	0.623	0.05
Mpp7	Scaffold protein	−1.210	0.006	−0.325	<0.0001	−1.184	0.001

FC, fold change; GPCR, G-protein coupled receptor; NFKB, nuclear factor kappa beta.

Liu et al. (2017) and Kurki et al. (2011) denoted genes as upregulated in ruptured tissue relative to unruptured tissue. Park et al. (2020) used the opposite convention, with genes denoted as upregulated in unruptured relative to ruptured tissue. We therefore have transformed the results of Park et al. (2020) to reflect the convention used in the other studies for ease of comparison.