Table 3.

List of upregulated and downregulated genes in common among two ovulation data sets and the chorioamniotic membrane rupture (CMR) data set.

Gene	Gene function	Ovulation (Liu et al., 2017) Log2FC	Ovulation (Liu et al., 2017) P-value	Ovulation (Park et al., 2020) Log2FC	Ovulation (Park et al., 2020) P-value	CMR (Nhan-Chang et al., 2010) Log2FC	CMR (Nhan-Chang et al., 2010) P-Value
Angptl4	Secreted protein	1.792	<0.0001	0.317	<0.0001	2.40	0.0009
Lox	Oxidase	1.924	0.0002	0.275	0.005	2.30	0.001
Pfkfb4	Kinase	2.596	<0.0001	0.447	<0.0001	1.50	0.009

FC, fold change.

Liu et al. (2017) and Nhan-Chang et al. (2010) denoted genes as upregulated in ruptured tissue relative to unruptured tissue. Park et al. (2020) used the opposite convention, with genes denoted as upregulated in unruptured relative to ruptured tissue. We therefore have transformed the results of Park et al. (2020) to reflect the convention used in the other studies for ease of comparison.