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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Alzheimers Dement. 2023 Jun 12;19(9):4150–4162. doi: 10.1002/alz.13347

Table 2.

Associations of baseline and slopes of cognition, motor abilities and total daily physical activity

Trivariate linear mixed-effects models in living older adults
Mot bl TDA bl Cog slp Mot slp TDA slp
Cog bl 0.46*
0.38*
0.18*
0.14*
0.35*
0.27*
0.17^
0.11NS
0.30*
0.19*
Mot bl - 0.43*
0.39*
0.31*
0.12^
0.06NS
−0.10NS
0.41*
0.26*
TDA bl - 0.03NS
−0.07NS
0.09NS
0.01NS
0.11NS
0.04NS
Cog slp - 0.63*
0.60*
0.53*
0.47*
Mot slp - 0.70*
0.69*

This table shows the results from two trivariate models using data from all participants in the current analytic cohort (N=1007). This model provides correlations of level of function at the analytic baseline and rate of change (slopes) for three phenotypes, cognitive function (Cog); motor abilities (Mot) and total daily physical activity (TDA). The first model was unadjusted for demographic covariates (age, sex and education) and the second model was adjusted for demographic covariates. Upper correlation in each cell is the correlation in a model without adjustment for the demographic covariates, age, sex and education. Lower correlation in each cell is the correlation derived from a model that adjusted for demographic covariates. Each models yield fifteen pairs of correlations derived from modeling level and slopes of function for the three clinical phenotypes based on repeated clinical total daily physical activity measures during follow-up of about six years. Three groups of correlations are obtained: a) the correlations of the three phenotypes at BL (yellow); b) the six correlations between level of function at BL for each of the three phenotypes with the rates of change (slopes) of each of the three phenotypes (orange) and c) the correlations of the rates of change (slopes) between each of the three phenotypes (blue). Each cell shows the estimated correlation:

*

<0.001

^

<0.01

NS >0.05.