Figure 5.

Knockdown of LMNA inhibited the migration and invasion of 786-O and SN12C cells. a) Representative results show that the migratory ability in siLMNA groups in 786-O and SN12C cells was greatly reduced; b) quantitative results of triplicates showing that migratory ability in siLMNA groups was severely reduced in both cell lines; c) Representative results of transwell invasion assays showing that invasiveness was severely impaired in both cell lines; d) quantitative results of duplicates showing that migratory ability was severely impaired in both 786-O and SN12C cells. At least two independent experiments were quantified and expressed as mean SD (*p < .05; **p < .01; ***p < .001).