Table 1.
Baseline characteristics of study participants one month after breakthrough infection.
| All | The young-adult Cohort | The Elder Cohort | |||
|---|---|---|---|---|---|
| All the elders | Fully vaccinated | Not–fully Vacccinated | |||
| N | 134 | 53 | 81 | 40 | 41 |
| Gender, male (%) | 67 (50) | 21 (39.6) | 46 (56.8) | 21 (52.5) | 25 (61) |
| Age, median (IQR) | 69 (39–81) | 33 (27–42) | 80 (69–88) | 75.5 (69–81.25) | 83 (69–91) |
| Comorbidities, N (%) | 87 (64.9) | 12 (22.6) | 75 (92.6) | 36 (90) | 39 (95.1) |
| Smoke, N (%) | 16 (11.9) | 3 (5.7) | 13 (16) | 10 (25) | 3 (7.3) |
| Alcohol Abuse, N (%) | 12 (9) | 3 (5.7) | 9 (11.1) | 8 (20) | 1 (2.4) |
| Obesity BMI > 28, N (%) | 11 (8.2) | 6 (11.3) | 5 (6.2) | 3 (7.5) | 2 (4.9) |
| hypertension, N (%) | 45 (33.6) | 5 (9.4) | 40 (49.4) | 24 (60) | 16 (39) |
| Heart Conditions, N (%) | 36 (26.9) | 0 (0) | 36 (44.4) | 17 (42.5) | 19 (46.3) |
| Cardiovascular Disease, N (%) | 23 (17.2) | 0 (0) | 23 (28.4) | 10 (25) | 13 (31.7) |
| Chronic Lung Disease, N (%) | 6 (4.5) | 0 (0) | 6 (7.4) | 2 (5) | 4 (9.8) |
| Vaccination ≥ 2doses, N (%) | 91 (67.9) | 51 (96.2) | 40 (49.4) | 40 (100) | 0 (0) |
| Heterogenous Booster | – | 21 (39.6) | – | – | – |
| Homogenous Booster | – | 19 (35.8) | – | – | – |
| Median (IQR) Days From Last Vaccination to Breakthrough Infection | 384.5(126.75–490) | 481(380–500) | 172(66–243) | 182(79–228.5) | 124.5(31.5–267.75) |
| WT, GMT [95%CI] | 489 (383–623) | 1182 (950–1470) | 274 (199–378) | 745 (560–991) | 104 (71–151) |
| BA.2, GMT [95%CI] | 726 (601–877) | 717 (561–915) | 733 (558–962) | 1071 (770–1490) | 506 (335–765) |
| BA.5, GMT [95%CI] | 585 (478–716) | 716 (569–901) | 513 (381–692) | 744 (530–1046) | 357 (222–574) |
| BA.7, GMT [95%CI] | 503 (427–593) | 570 (469–692) | 464 (364–592) | 605 (467–782) | 358 (239–537) |
| BQ.1.1, GMT [95%CI] | 236 (193–289) | 353 (267–467) | 181 (138–238) | 233 (172–314) | 142 (91–223) |
| CH.1.1, GMT [95%CI] | 258 (209–318) | 196 (154–250) | 308 (227–420) | 303 (208–441) | 314 (190–519) |
| XBB.1.5, GMT [95%CI] | 157 (132–187) | 222 (178–277) | 125 (99–159) | 149 (113–196) | 106 (72–156) |
Abbreviations: IQR: Interquartile Rangel; WT wild type; GMT: Geometric Mean Titre; CI: Confidence Interval.