Table 1.
Contributing cohorts
| H70 | HELIAD | Invece.Ab | KLOSCAD | LEILA 75+ | MAS | MMAP | PATH | ZARADEMP | All | |
|---|---|---|---|---|---|---|---|---|---|---|
| Reference | Thorvaldsson et al.33 [2017] | Dardiotis et al.32 [2014] | Guaita et al.31 [2013] | Han et al.35 [2018] | Riedel-Heller et al.27 [2001] | Sachdev et al.28 [2010] | Dominguez et al.34 [2018] | Anstey et al.30 [2012] | Lobo et al.29 [2011] | - |
| Schedule | ||||||||||
| Start | 2000 | 2009 | 2009 | 2010 | 1997 | 2005 | 2011 | 2001 | 1994 | - |
| End | Ongoing | Ongoing | 2015 | 2020 | 2014 | Ongoing | Ongoing | 2021 | Ongoing | - |
| Interval* | 2–4 years | 3 years | 2 years | 2 years | 5 years | 2 years | 5 years | 4 years | 1–5 years | - |
| Location | Gothenburg, Sweden | Larissa and Marousi, Greece | Milan, Italy | Nationwide, South Korea | Leipzig, Germany | Sydney, Australia | Marikina, Philippines | Canberra and Queanbeyan, Australia | Zaragoza, Spain | - |
| Participants | ||||||||||
| Ethnicity | White | White | White | Asian | White | White | Asian | White | White | - |
| Age† | 73.9 ± 4.9 | 73.1 ± 5.7 | 72.2 ± 1.3 | 70.2 ± 6.9 | 81.5 ± 5.0 | 86.9 ± 4.2 | 69.6 ± 6.6 | 75.2 ± 1.6 | 73.5 ± 9.7 | 72.8 ± 7.9 |
| Numbers | ||||||||||
| All | 1018 | 2062 | 1321 | 6818 | 1265 | 465 | 1367 | 361 | 4803 | 19480 |
| Included | 796 | 1961 | 1304 | 6218 | 814 | 406 | 672 | 354 | 4669 | 17194 |
| Dementia | 20 | 90 | 39 | 254 | 85 | 91 | 57 | 26 | 199 | 861 |
| AD | 10 | 70 | 13 | 194 | 50 | 65 | 49 | 23 | 131 | 605 |
| VaD | 4 | 7 | 13 | 36 | 27 | 13 | 6 | 1 | 49 | 156 |
| OD | 6 | 13 | 13 | 24 | 8 | 13 | 2 | 2 | 19 | 100 |
| Family history§ | ||||||||||
| Parental | 205(25.8) | 215(11.0) | 103(7.9) | 582(9.4) | 96(11.8) | 63(15.5) | 121(18.0) | 67(18.9) | 301(6.4) | 1753(10.2) |
| Maternal | 144(18.1) | 159(8.1) | 90(6.9) | 481(7.7) | 64(7.9) | 44(10.8) | 106(15.8) | 51(14.4) | 199(4.3) | 1338(7.8) |
| Paternal | 80(10.1) | 61(3.1) | 14(1.1) | 127(2.0) | 34(4.2) | 19(4.7) | 35(5.2) | 19(5.4) | 111(2.4) | 499(2.9) |
| Both | 19(2.4) | 4(0.2) | 1(0.1) | 26(0.4) | 2(0.2) | 0(0.0) | 20(3.0) | 3(0.8) | 9(0.2) | 84(0.5) |
H70, Gothenburg H70 Birth Cohort Studies; HELIAD, Hellenic Longitudinal Investigation of Aging and Diet; Invece.Ab, Invecchiamento Cerebrale in Abbiategrasso; KLOSCAD, Korean Longitudinal Study on Cognitive Aging and Dementia; LEILA75+, Leipzig Longitudinal Study of the Aged; MAS, The Sydney Memory and Ageing Study; MMAP, Marikina Memory and Aging Project; PATH, Personality And Total Health through life; ZARADEMP, Zaragoza Dementia Depression Project; AD, Alzheimer’s disease; VaD, vascular dementia; OD, other types of dementia
*
follow-up interval
†
age (years) at the baseline assessment presented as mean ± standard deviation
§
presented as numbers of participants (percentage)