Table 2.
Demographic and clinical characteristics of the participants
| Characteristics | Parental history | Paternal history | Maternal history | ||||||
|---|---|---|---|---|---|---|---|---|---|
| No (N = 15441) |
Yes (N = 1753) |
p* | No (N = 16695) |
Yes (N = 499) |
p* | No (N = 15856) |
Yes (N = 1338) |
p* | |
| Age, years | 72.8 ± 7.9 | 71.4 ± 7.7 | <0.001 | 72.8 ± 7.9 | 71.4 ± 7.7 | <0.001 | 72.9 ± 7.9 | 70.8 ± 7.3 | <0.001 |
| Female, N(%) | 9110(59.0) | 1062(60.6) | 0.184 | 9883(59.2) | 293(58.7) | 0.838 | 9355(59.0) | 818(61.1) | 0.126 |
| Educational level, years | 8.1 ± 4.7 | 9.7 ± 4.7 | <0.001 | 8.1 ± 4.7 | 9.7 ± 4.7 | <0.001 | 8.0 ± 4.7 | 9.7 ± 4.5 | <0.001 |
| Hypertension, N(%) | 8956(58.0) | 919(52.4) | <0.001 | 9616(57.6) | 259(51.9) | 0.011 | 9181(57.9) | 698(52.2) | <0.001 |
| Diabetes mellitus, N(%) | 2671(17.3) | 282(16.1) | 0.212 | 2872(17.2) | 81(16.2) | 0.557 | 2743(17.3) | 215(16.1) | 0.282 |
| Apolipoprotein E ε4 (+)*, N(%) | 3289(21.3) | 498(28.4) | <0.001 | 3673(22.0) | 134(26.8) | 0.056 | 3393(21.4) | 385(28.8) | < 0.001 |
Age and educational level are presented as mean ± standard deviation.
*
Student t test for continuous variables and chi square test for categorical variables *9397 particpants (8296 without parental history and 1101 with parental history) had data on apolipoprotein E genotype