Table 4. Average costs of different therapeutic options for functional dyspepsia.
Prices of screening and diagnostic tests performed in Washington, DC (selected as an example) were obtained from a publicly available website (https://www.fairhealthconsumer.org/) and include facility fees. Estimates are based on the 80th percentile and correspond to in-network costs. Prices of medications were obtained from a publically available website (https://www.goodrx.com/) that offers discounted coupons.
| Methods to exclude or treat organic dyspepsia | ||
|---|---|---|
| CPT code/example of treatment | US $ | |
| EGD | ||
| EGD | 43235 | 2635 |
| Clarithromycin triple treatment for Hp | Pantoprazole (40 mg QD) Clarithromycin (500 mg BID) Amoxicillin (1 g BID) |
9.5 / 2 weeks 10.5 / 2 weeks 13 / 2 weeks |
| Bismuth quadruple therapy for Hp | Pantoprazole (40 mg QD) Bismuth subsalicylate (524 mg QID) Tetracycline (500 mg, QID) Metronidazole (250 mg QID) |
9.5 / 2 weeks 8.3 / 2 weeks 50.2 / 2 weeks 11.5 / 2 weeks |
| Methods for diagnosis and treatment of functional dyspepsia | ||
| CPT code/example of treatment | US $ | |
| Gastric emptying scintigraphy | 78264 | 1962 |
| Gastric emptying breath test | 0106U | 150 to 450 |
| Gastric Accommodation test | 78262 | 2261 |
| Proton pump inhibitor | Pantoprazole (40 mg BID) | 19 / month |
| H2 receptor antagonist | Famotidine (20 mg BID) | 11.7 / month |
| Metoclopramide | Metoclopramide (5 mg TID) | 4.0 / month |
| Central Neuromodulator: TCA or SSRI | Amitriptyline (25 mg QD) | 1.6 / month |
| Pyridostigmine | Pyridostigmine (60 mg TID) | 17.0 / month |
| Buspirone | Buspirone (5 mg TID) | 2.7 / month |
| Ondansetron | Ondansetron (4 mg TID) | 25.4 / month |
| Promethazine | Promethazine (12.5 mg QID) | 13.5 / month |
| FDgard | 2 tabs TID | 149.7 / month |
BID: twice a day; CMS: Centers for Medicare and Medicaid services; CPT: Current Procedural Terminology; EGD: Esophagogastroduodenoscopy; Hp: helicobacter pylori; QD: once a day; QID: four times a day; NA: not available; SSRI: selective serotonin reuptake inhibitor; TCA: tricyclic antidepressants; TID: three times a day.