Table 1.

Parameters used in the MOXE model, as determined from current literature for healthy populations.

Variable	Description	Literature value
$S_A/V_g (cm-1)$	Alveolar surface area to volume ratio20	250
$d \left(\mu m\right)$	Total septum thickness28	12
$\delta \left(\mu m\right)$	Air-blood membrane thickness29	2.22
$t_X \left(s\right)$	Capillary transit time20	1.6
$D (cm2/s)$	Diffusion coefficient of dissolved xenon59	3.3×10−6
$\lambda$	Ostwald solubility of xenon in lung parenchyma22	0.2
${\lambda }_{\mathit{\text{RBC}}}$	Ostwald solubility of xenon in RBCs60	0.19
${\lambda }_P$	Ostwald solubility of xenon in plasma60	0.091
$H{b}^0 (g/dL)$	Healthy reference value for volume of venous hemoglobin19	14
$h_r$	Ratio of regional pulmonary Hct to venous Hct25	0.9
$a (dL/g)$	$h_r\cdot$ (Hct to Hb conversion factor61)	(0.9) ⋅ (2.953×10−2)