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. 2023 Jun 22;10(9):1306–1316. doi: 10.1002/mdc3.13813

TABLE 4.

Causes of copper deficiency (adapted from Myint et al)

Causes Diseases
Drug‐related Excessive zinc ingestion (from dental paste, excessive oral supplementation or in Wilson's disease treatment) or iron supplements
Decreased/inadequate intake Anorexic patients, malnutrition, Kwashiorkor, vegetarian, parenteral or enteral nutrition without adequate copper supplements
Increase copper loss or inadequate absorption Inflammatory bowel disease (Crohn's disease, ulcerative colitis), celiac disease, bypass surgery, gastrectomy, prolonged diarrhea, protein‐losing enteropathy, tropical and non‐tropical spure
Increase demand Pregnant women, lactating women, premature infants, children
Hereditary Menkes disease