TABLE 1.
Results of galactomannan antigen assay and nested PCR with sera of patients with various forms of pulmonary aspergillosis
| Patient no. | Age (yr) | Sexa | Aspergillosis type | Underlying disease(s)b | Galactomannan antigenc | Nested PCRc | Cultured straind |
|---|---|---|---|---|---|---|---|
| 1 | 84 | M | Aspergilloma | Old pulmonary tuberculosis | − | − | A. fumigatus |
| 2 | 67 | M | Aspergilloma | Pneumoconiosis and tuberculosis | − | − | A. fumigatus |
| 3 | 74 | M | Aspergilloma | Pneumoconiosis and tuberculosis | − | − | Aspergillus niger |
| 4 | 70 | M | Aspergilloma | Old pulmonary tuberculosis | − | − | NP |
| 5 | 76 | M | Aspergilloma | Old pulmonary tuberculosis | − | − | NP |
| 6 | 73 | M | Aspergilloma | Old pulmonary tuberculosis | − | − | NP |
| 7 | 55 | M | Aspergilloma | Pulmonary cyst | − | + | A. fumigatus |
| 8 | 78 | M | Aspergilloma | Old pulmonary tuberculosis | − | − | NP |
| 9 | 57 | M | Aspergilloma | Old pulmonary tuberculosis | − | − | A. fumigatus |
| 10 | 65 | M | CNPA | IIP | − | + | A. fumigatus |
| 11 | 68 | M | CNPA | Old pulmonary tuberculosis | + | + | A. fumigatus |
| 12 | 64 | M | CNPA | Diabetes mellitus | + | + | Aspergillus sp. |
| 13 | 73 | M | CNPA | Old pulmonary tuberculosis | − | − | Aspergillus sp. |
| 14 | 67 | M | CNPA | Old pulmonary tuberculosis | − | + | Aspergillus sp. |
| 15 | 69 | M | CNPA | Pulmonary cyst | + | − | A. fumigatus |
| 16 | 42 | M | Proven IPA | AML | + | + | A. fumigatus |
| 17 | 52 | F | Proven IPA | Nephrotic syndrome | + | + | A. fumigatus |
| 18 | 37 | M | Proven IPA | ATL | + | + | A. niger |
| 19 | 18 | M | Proven IPA | CGD | + | + | A. fumigatus |
| 20 | 65 | F | Presumptive IPA | AML | − | + | NP |
| 21 | 48 | F | Presumptive IPA | ATL | − | − | NP |
| 22 | 45 | M | Presumptive IPA | AML | − | + | NP |
| 23 | 60 | M | Presumptive IPA | AML | − | + | NP |
| 24 | 76 | M | Presumptive IPA | Malignant lymphoma | − | + | NP |
| 25 | 68 | F | Presumptive IPA | AML | + | + | NP |
| 26 | 21 | M | Presumptive IPA | CGD | − | − | NP |
| 27 | 68 | M | Presumptive IPA | Malignant lymphoma | + | + | NP |
| 28 | 85 | M | Pyothorax | Unknown | + | + | A. niger |
| 29 | 60 | F | Pyothorax | Wegener’s granulomatosis | − | − | A. fumigatus |
| 30 | 86 | M | Pyothorax | Unknown | + | − | A. fumigatus |
a
M, male; F, female.
b
IIP, idiopathic interstitial pneumonia; AML, acute myelogenous leukemia; CGD, chronic granulomatous disease; ATL, adult T-cell leukemia.
c
+, positive; −, negative.
d
NP, not performed.