Table 2.

Effect of ACCESS antibiotics on gastrointestinal dysbiosis.

Antibiotic	Experimental Model	Bacteria Decreased	Bacteria Increased	Time for Gut to Recover	Long Term Impacts
Doxycycline [57]	Human	Enterobacteriaceae, Enterococcus spp., Escherichia coli, Streptococcus spp., and Fusobacterium spp.	Not Applicable	9 days after treatment	Not Applicable
Doxycycline [59]	Human	Bifidobacterium	Not Applicable	Not Applicable	Increase in tetracycline resistance
Doxycycline [62]	Human	Escherichia coli, Enterococcaceae	Not Applicable	4 weeks after 16-week treatment	Increased doxycycline resistance
Tetracycline [60]	Honeybee	Lactobacillus, Frischella, Commensalibacter, Bartonella, Gilliamella, Snodgrassella	Not Applicable	Did not recover	Gut microbiota did not recover in treated bees. This could harm the colony as contact with hive mates is a major contributor to bee microbiota
Tetracycline [61]	Honeybee	Bifidobacterium, Firm-4, Firm-5, Snodgrassella alvi, Alpha 2.1, Frischella perrara, Lactobacillus kunkeei, Bartonella apis	Serratia, Halomonadaceae, Gilliamella apicola	32% of treated bees recovered 3 days after treatment	Tetracycline-treated bees have increased mortality