Table 2.
Photodynamic action of curcumin against various cancer cells in vitro.
| Type of Cancer Cells | Type of Light and Formula Used | Ref |
|---|---|---|
| Oral cancer | ||
| HN cells | VIS, 5500 lx, UVA, curcumin solution | [101] |
| Skin cancer cells | ||
| A431/xenograft | VIS, 5500 lx, UVA, curcumin solution | [1] |
| A431 | VIS, curcumin solution | |
| A431 | VIS/PEGylated lipid nanocarrier in vitro | [102] |
| SCC | 380–550 nm, Lip-cur | [74] |
| Melanoma | ||
| G-361, A375 | VIS, 5500 lx, UVA, curcumin solution | [103] |
| A375 | combination 630 nm + 405 nm polarized blue light, solution DMSO | [104] |
| A735, C32 | [105] | |
| MugMel2 | VIS (380–550 nm), Lip-cur | [74] |
| Bladder cancer | ||
| RT112,UMUC3, TCCSUP | VIS, 5500 lx, curcumin solution | [106] |
| RT112,UMUC3, TCCSUP | VIS, 5500 lx, curcumin solution | [107] |
| Colon cancer | ||
| SW620, HT29 | 470 nm, curcumin solution | [108] |
| CaCo2 | 5-ALA + 635 nm diode laser system/solution DMSO | [109] |
| CaCo2 | 424 nm, CAgNPs | [85] |
| mouse colorectal-CT26 | 450 nm, F127-curcumin micelles | [110] |
| Prostate cancer | ||
| PC3 | 5-ALA + 635 nm diode laser system/solution DMSO | [109] |
| LNCaP | 430 nm LED, curcumin solution | [111] |
| Kidney cancer | ||
| A498, Caki1, KTCTL-26 | VIS, 5500 lx, curcumin solution | [112] |
| A498, Caki1, KTCTL-26 | VIS, 5500 lx, curcumin solution | [113] |
| Liver cancer | ||
| SMMC-7721 | 430 nm, curcumin solution | [114] |
| HuH6, HepT1,Hep-G2, HC-AFW1 | 390–440 nm, curcumin solution | [115] |
| Cervical cancer | ||
| HeLa | VIS (400–700 nm), curcumin solution | [116] |
| Me180 | 445 nm laser, Cur-LDH | [117] |
| SiHa, CasKi | 447 nm LED, nano-emulsion | [118] |
| Lung cancer | ||
| A549 | 430 nm LED, Cur-SLN | [119] |
| A549 | 457 nm LED, PLGA nanoparticles | [120] |
| Ovarian cancer | ||
| SK-OV3 | 457 nm, 620 nm LED), Cur-NP | [121] |
| Breast cancer | ||
| MCF-7 | 430 nm, Cur-NLCs | [122] |
| MCF-7 | 440 nm LED, nano-emulsion | [123] |
| MDA-MB-231 | curcumin-LDH nanoparticles | [124] |
| mouse 4T1 | Cur NDs | [125] |
| mouse 4T1 | Photothermal/Au-Cur nanostructure | [126] |
| Gastric cancer | ||
| MKN45 | 460 nm LED, nano-encapsulated curcumin with EGF | [127] |
VIS—visible light, Lip-cur—liposomal curcumin, Cur-SLN—curcumin–solid–liquid nanomaterial, Cur-AgNPs—curcumin conjugated with the silver nanoparticles, Cur-NLCs—curcumin nano-lipid carriers, EGF—epidermal growth factor, Cur-NP, Cur NDs—curcumin in nanoparticles, Au-Cur—gold–curcumin nanostructure.