Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Molecular mechanisms of β-lactam resistance in S. aureus. (i) Inactivation of antibiotic: hydrolysis of the amide bond of penicillin G by β-lactamase, rendering the antibiotic inactive [7]. (ii) Target bypass: the TPase activity of PBP2 targeted by β-lactams is taken over by acquired PBP2a in MRSA, which is not inhibited by β-lactams [12].
