Table 1.
Characteristics of excessive alcohol drinkers (EADs) and healthy controls.
Variable | EAD Patients (n = 20) | Controls (n = 22) | p-Value |
---|---|---|---|
Age (years) Sex (M/F) * |
46.6 (10.5) 15/5 (75%/25%) |
42.3 (14.1) 15/7 (68.2%/31.8%) |
0.27 0.63 |
Total Bilirubin (mg/dL) | 0.7 (0.8) | 0.6 (0.3) | 0.48 |
AST (U/L) | 43.0 (38.0) | 20.4 (8.5) | 0.02 |
ALT (U/L) | 49.3 (56.2) | 23.3 (8.2) | 0.05 |
ALP (U/L) | 86.0 (35.7) | 52.3 (12.8) | 0.001 |
LDH (U/L) | 171.4 (42.9) | 185.6 (64.4) | 0.42 |
GGT (U/L) | 194.3 (303.8) | 23.5 (20.7) | 0.02 |
Proteins (g/dL) | 7.3 (0.6) | 7.5 (0.4) | 0.24 |
Albumin (g/dL) | 6.0 (1.4) | 4.7 (0.2) | 0.001 |
Ferritin (ng/mL) | 498.9 (562.4) | 151.3 (112.7) | 0.01 |
Hemoglobin (g/dL) | 15.2 (1.5) | 15.3 (1.3) | 0.74 |
Hematocrit (%) | 42.0 (9.9) | 43.5 (7.4) | 0.57 |
Erythrocyte MCV (fL) | 95.5 (6.8) | 89.2 (4.0) | 0.001 |
Erythrocyte MCH (pg) | 33.1 (2.8) | 30.5 (1.6) | 0.001 |
Leukocytes (×103 cells/μL) | 7.6 (1.9) | 6.3 (1.4) | 0.001 |
Neutrophils (×103 cells/μL) | 4.4 (1.7) | 3.3 (1.0) | 0.008 |
Lymphocytes (×103 cells/μL) | 2.2 (0.6) | 2.3 (0.6) | 0.47 |
Platelets (×103 cells/μL) | 214.9 (73.9) | 262.5 (67.8) | 0.03 |
Total cholesterol (mg/dL) | 212.9 (41.0) | 220.8 (35.7) | 0.51 |
Triglycerides (mg/dL) | 126.4 (68.6) | 115.4 (50.4) | 0.55 |
Prothrombin activity (%) | 90.8 (9.3) | 94.9 (6.1) | 0.11 |
APTT (seconds) | 37.3 (5.1) | 34.7 (2.2) | 0.07 |
Fibrinogen (mg/dL) | 372.1 (111.8) | 311.0 (57.8) | 0.05 |
D-Dimer (μg/mL) | 0.5 (0.3) | 0.4 (0.7) | 0.70 |
Results are expressed as mean (standard deviation) or as * number of cases (percentage). AST, aspartate aminotransferase. ALT: alanine aminotransferase. ALP: alkaline phosphatase. EAD: excessive alcohol drinker. F: female. LDH: lactate dehydrogenase. GGT: gamma-glutamyl transferase. M: male. MCV: mean corpuscular volume. MCH: mean corpuscular hemoglobin. APTT: activated partial thromboplastin time.