Table 1.

Outline of study procedures.

Procedures	Telephone Call	Baseline Visit	First Visit	Visit 2–Visit 17	Final Visit	6-Month Follow-Up
Eligibility Assessment	✓
Informed consent		✓
Blood Tests: Full blood count, Urea and electrolytes, Liver function tests, HbA1c (if diabetic)
Demographics: Age, Gender, Marital status, Employment status, Educational level, Ethnicity		✓
Medical History: Chronic pain symptom duration, Co-morbidities, Medications		✓				✓
Measurements: Height, Weight, BMI, Blood pressure, Heart rate, Oxygen saturations		✓			✓ ✓
Participant-reported outcomes measures (PROMs):       Brief Pain Inventory       Widespread Pain Index/Symptom Severity Score       Fatigue Severity Scale       Jenkins Sleep Questionnaire       Patient Global Impression of Change       Revised Fibromyalgia Impact Questionnaire       Hospital Anxiety and Depression Scale		✓  ✓  ✓  ✓  ✓  ✓			✓  ✓  ✓  ✓  ✓  ✓  ✓	✓  ✓
Performance-based outcome measures (PBOMs):       Tender Point Count       Stroop Test		✓  ✓			✓  ✓
Treatment			✓ ✓	✓	✓
Weekly Numerical Rating Scale (NRS) Participant-reported experience measure (PREM)				✓	✓  ✓ ✓
Audio-recorded qualitative interviews (optional)			✓	✓	✓ ✓