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. 2023 Aug 28;11(9):2411. doi: 10.3390/biomedicines11092411

Table 1.

The classification of long non-coding RNAs (lncRNAs) according to the genomic locations of Their genes.

Classification Description
Sense lncRNAs Transcribed from the same strand as a protein-coding gene and may overlap entirely or partially with the gene [12].
Antisense lncRNAs Transcribed from the opposite strand of a protein-coding gene and may overlap with exons or introns [13].
Intronic lncRNAs Located within the introns of a protein-coding gene but transcribed independently [14].
Intergenic lncRNAs Situated between protein-coding genes and do not overlap with them. Also known as long intergenic non-coding RNAs (lincRNAs) [15].
Bidirectional lncRNAs Transcribed in close proximity to a protein-coding gene but in the opposite direction [16].
Enhancer lncRNAs (eRNAs) Associated with enhancer regions and may regulate the activity of enhancers, influencing gene expression [17].