Skip to main content
. 2023 Sep 12;11(9):2513. doi: 10.3390/biomedicines11092513

Figure 8.

Figure 8

mRNA expression of TIMPs (1–4) and MMPs (2, 3, 9, 14) in 3D cultured human corneal stroma fibroblasts (HCSFs). In the absence or presence of 1 nM or 5 nM TGF-β2, 3D HCSF spheroids were prepared during a 6-day culture, and the mRNA expression of TIMPs (1–4) and MMPs (2, 3, 9, 14) was measured by a qPCR analysis. All experiments were performed in duplicate using fresh preparations (n = 15, each). Data are presented as the arithmetic mean ± standard error of the mean (SEM). * p < 0.05, ** p < 0.01 (ANOVA followed by a Tukey’s multiple comparison test).