Figure 7.

The mean differences in re-isolated indicator bacterial colony counts (log₁₀ CFU/mL) from femoral bone marrow contents and screws used in animals between the experimental groups. Section (a) shows the colony counts from femoral bone marrow, and section (b) shows colony counts from suspensions made using screws from animals. The CFU values of all groups were analyzed using a Kruskal–Wallis test followed by Dunn’s test for post-hoc testing. The experimental groups are as follows: PBS only, treated with sterile PBS; PBS + SP, treated with sterile PBS after bacterial inoculation; MRS + SP, treated with 20-fold concentrated sterile MRS broth after bacterial inoculation; DA + SP, treated with clindamycin (11 mg/kg) after bacterial inoculation; CFS + SP, treated with 20-fold concentrated L. animalis SWLA-1-derived CFS after bacterial inoculation. Significant differences are denoted by asterisks (*: p < 0.05, **: p < 0.01, ***: p < 0.001, ****: p < 0.0001). PBS, Phosphate buffered saline; SP, Staphylococcus pseudintermedius; MRS, Man Rogosa and Sharpe broth; DA, clindamycin; CFS, cell-free supernatant. The outliers were present by the bullets in the figure. The mean of observed data in each experimental group was present by the horizontal bold line in the figure.