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. 2023 Sep 19;15(18):4629. doi: 10.3390/cancers15184629

Figure 8.

Figure 8

Participation of acetylcholinesterase in apoptosome formation. Acetylcholinesterase binds to caveolin-1, which allows the binding of Apaf-1 to cytochrome C, which consequently causes cleavage of procaspase-9 to produce the active form. Then, caspase 9 promotes the activation of the caspase cascade and apoptosis. Created with Biorender.com (accessed on 12 June 2023).