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Mechanisms of environmental toxicants causing lung cancer. DNAdsb: double-strand DNA breaks, ROS: reactive oxygen species, NF-κB: nuclear factor kappa B, Nrf2: nuclear factor erythroid 2–related factor 2, IL-1/6 interleukin-1/6, TNF-α: tumor necrosis factor-alpha, Caspase: cysteine-dependent aspartate-directed proteases, CAT: Catalase, MDA: malondialdehyde, TAC: Total antioxidant capacity.
