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Macrotrabecular massive hepatocellular carcinoma. (a) A nodular expanding brown–tan tumor is present. (b) The thick trabeculae of more than 10 cells are surrounded by vascular spaces (hematoxylin–eosin stain, ×100). (c) The vessels that encapsulate tumor clusters pattern, which encapsulates and separates individual tumor clusters, are present (immunohistochemical stain for CD34, ×100).
