Table 2.

Upregulated and Downregulated Proteins Between Matched Delirium and Non-Delirium Samples.

Increased in Delirium
Full Name of Protein	UniProt	Gene Symbol	tFC	p-Value
Aggrecan core protein	P16112	ACAN	1.79	0.013
Cofilin-1	P23528	CFL1	1.62	0.041
C-X-C motif chemokine 11	O14625	CXCL11	1.46	0.047
Histone H2A.z	P0C0S5	H2AFZ	1.44	0.020
Mucin-1	P15941	MUC1	1.39	0.039
Nicotinamide phosphoribosyltransferase	P43490	NAMPT	1.36	0.029
Insulin	P01308	INS	1.35	0.019
CD97 antigen	P48960	CD97	1.32	0.006
Inducible T-cell costimulator	Q9Y6W8	ICOS	1.31	0.028
Protein deglycase DJ-1	Q99497	PARK7	1.31	0.030
Protein FAM107B	Q9H098	FAM107B	1.29	0.028
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	P28907	CD38	1.29	0.048
Beta-nerve growth factor	P01138	NGF	1.2	0.020
Peptidyl-prolyl cis-trans isomerase F, mitochondrial	P30405	PPIF	1.17	0.035
Thrombopoietin	P40225	THPO	1.12	0.010
Decorin	P07585	DCN	1.09	0.013
MHC class I polypeptide-related sequence A	Q29983	MICA	0.9	0.011
Hyaluronan and proteoglycan link protein 1	P10915	HAPLN1	0.86	0.042
Decreased in Delirium
Cathepsin L2	O60911	CTSV	−1.47	0.048
Granulysin	P22749	GNLY	−1.43	0.045
C-X-C motif chemokine 6	P80162	CXCL6	−1.36	0.017
C-C motif chemokine 2	P13500	CCL2	−1.34	0.030
Matrix metalloproteinase-14	P50281	MMP14	−1.29	0.030
Moesin	P26038	MSN	−1.24	0.014
Chordin-like protein 1	Q9BU40	CHRDL1	−1.22	0.035
Activated Protein C	P04070	PROC	−1.21	0.015
C-C motif chemokine 28	Q9NRJ3	CCL28	−1.21	0.015
Cathepsin D	P07339	CTSD	−1.15	0.021
Follistatin-related protein 1	Q12841	FSTL1	−1.12	0.040
Insulin-like growth factor-binding protein 2	P18065	IGFBP2	−1.07	0.028
Tyrosine-protein phosphatase non-receptor type 6	P29350	PTPN6	−1.04	0.044
Protein kinase C alpha type	P17252	PRKCA	−1.02	0.035

tFC = Tukey Fold Change, t-test p-value < 0.05 is considered significant.