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. 2023 Sep 14;13(9):1318. doi: 10.3390/brainsci13091318

Table 1.

Summary of upregulated and downregulated genes identified from a microarray analysis of mRNA obtained from brain tissues and blood samples in AD and PD, as well as from CSF in MS. Arrows represent the direction of changes of the gene levels.

AD Brain
tissue
Inline graphicHDAC1, WWTR1, ITGB1, PDGFRB, PLOD1, MAP4K4, NFKBIA, TYROBP, GSN, TIMP1
Inline graphicSIRT3, RAB7A, BDNF, VLDLR, APLP2
Blood Inline graphicVCAM1, TYK2, TCIRG1, PPP3CB, SNCB, SACS, GSN, TIMP1
Inline graphicCTSD, RPL11, SNCA, FKBP1B, BDNF, VLDLR, APLP2
PD Brain
tissue
Inline graphic SRRM2
Inline graphicMAPK8, CDC42, NDUFS1, COX4I1, SDHC
Blood Inline graphicLILRB3, CSF3R, SRRM2
Inline graphic ICAM1
MS CSF Inline graphicNLRP3, LILRB2, C1QB, CD86, C1QA, CSF1R, IL1B, TLR2