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. Author manuscript; available in PMC: 2024 Aug 15.
Published in final edited form as: Neuroimage. 2023 Jun 15;277:120224. doi: 10.1016/j.neuroimage.2023.120224

Table 3:

Comparisons of properties among different HRF modeling approaches.

Individual level

Canonical HRF Sampled HRF Smooth HRF
shape assumption: (a priori) fixed adaptive, data-driven
basis: Gamma variates deconvolution with piecewise linear splines (e.g., TENT, FIR)
dimension: scalar (0D) vector (1D) of equally spaced samples
trial-level effects: possible difficult

Population level

Canonical HRF Sampled HRF Smooth HRF
dimension: scalar (0D) vector (1D) of equally spaced samples smooth curve (1D)
interpretability: high: signed peak magnitude moderate: detailed shape features, but relies on visual examination
robustness: low: inflexible and vulnerable to under-fitting moderate: adaptive but vulnerable to over-fitting high: adaptive and regularized