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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: Acta Physiol (Oxf). 2023 Jun 19;238(4):e14014. doi: 10.1111/apha.14014

Figure 4: Ablation of RPCs and CoRL with DTA:

Figure 4:

Figure 4:

(A-C) Whole tile scan images of kidney sections from 3W old WT and DTA-positive animals under basal state. GFP+ renin lineage cells are significantly reduced in the animals expressing DTA and more pronounced in the Ren1dCre;ROSA-DTA;mTmG mice (Scale bar 500μm, 50μm) (D) Quantification on the GFP+ area fraction of the CoRL (P<0.01; ****P<0.0001).