Table 2.
Numbers of RES with low stringencies for threshold values. The percentage of the RES in ADAR1KO in comparison to WT indicates a reduction in the number (#) of RES upon genetically ablating ADAR1, as expected. N/A represents not applicable.
| Sample Condition | Aligner | Tool | # RES | % (ADAR1KO/WT) |
|---|---|---|---|---|
| WT | BWA | RED-ML | 17,110 | |
| ADAR1KO | BWA | RED-ML | 7228 | 42.24 |
| WT | HISAT2 | RED-ML | 6158 | |
| ADAR1KO | HISAT2 | RED-ML | 918 | 14.91 |
| WT | STAR | RED-ML | 17,309 | |
| ADAR1KO | STAR | RED-ML | 2267 | 13.10 |
| WT | BWA | REDItools2 | 344,646 | |
| ADAR1KO | BWA | REDItools2 | 257,445 | 74.70 |
| WT | HISAT2 | REDItools2 | 174,481 | |
| ADAR1KO | HISAT2 | REDItools2 | 110,643 | 63.41 |
| WT | STAR | REDItools2 | 246,040 | |
| ADAR1KO | STAR | REDItools2 | 157,254 | 63.91 |
| WT | BWA | SPRINT | 27,707 | |
| ADAR1KO | BWA | SPRINT | 919 | 3.32 |
| WT | HISAT2 | SPRINT | 6903 | |
| ADAR1KO | HISAT2 | SPRINT | 58 | 0.84 |
| WT | STAR | SPRINT | N/A | |
| ADAR1KO | STAR | SPRINT | N/A | N/A |
| WT | BWA | JACUSA2 | 27,388 | |
| ADAR1KO | BWA | JACUSA2 | 18,606 | 67.93 |
| WT | HISAT2 | JACUSA2 | 13,252 | |
| ADAR1KO | HISAT2 | JACUSA2 | 7739 | 58.40 |
| WT | STAR | JACUSA2 | 20,455 | |
| ADAR1KO | STAR | JACUSA2 | 12,431 | 60.77 |