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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Neurogastroenterol Motil. 2023 Jun 25;35(10):e14629. doi: 10.1111/nmo.14629

Figure 1. B. subtilis R0179 treatment increases colonic Trp and 5-HIAA levels.

Figure 1.

To determine whether one week of treatment with the Trp-synthesizing strain B. subtilis R0179 alters colonic metabolite levels in mice, distal colon tissue was collected at day 7 upon euthanasia and analyzed by HPLC. Mice that received B. subtilis (n=11) displayed significantly higher levels of colonic Trp and 5-HIAA compared to vehicle control mice (n=8). Data are shown as mean ± SEM. Unpaired Student’s t-test. * p < 0.05.