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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Gastroenterology. 2023 Jun 2;165(3):656–669.e8. doi: 10.1053/j.gastro.2023.05.041

Figure 6.

Figure 6.

Transcriptomic changes orchestrated by DHPS in CECs. (A) RNA extracted from CECs from Dhpsfl/fl and DhpsΔepi (n = 3 mice per group) was sequenced, and the volcano plot corresponding to the DEGs in DhpsΔepi mice compared to Dhpsfl/fl animals was generated using R; red dots correspond to genes significantly (P < .05) up- or downregulated by 2–fold or more. All the genes are provided in Supplementary Table 4. (B) Pathway analysis of DEGs by GSEA; the complete list of pathways is shown in Supplementary Table 5.