Table 1.
Demographic, clinical, and behavioral characteristics of participants offered PrEP between 14–32 weeks gestation (n=2949)
| N | n (%) or Median (IQR) | |
|---|---|---|
|
| ||
| Demographic characteristics | ||
|
| ||
| Study arm | 2949 | |
| Universal PrEP offer | 1488 (50.5) | |
| Targeted PrEP offer | 1461 (49.5) | |
|
| ||
| Age (years) | 2948 | 24.2 (21.0, 28.6) |
|
| ||
| Age category (years) | 2948 | |
| <24 | 1392 (47.2) | |
| ≥24 | 1556 (52.8) | |
|
| ||
| Currently married | 2914 | 2527 (86.7) |
|
| ||
| Education (years) | 2886 | 10 (8, 12) |
|
| ||
| Education category (years) | 2886 | |
| <12 | 1843 (63.9) | |
| ≥12 | 1043 (36.1) | |
|
| ||
| Regular employment | 2904 | 418 (14.4) |
|
| ||
| People per room | 2917 | 1.7 (1, 2.5) |
|
| ||
| 2+ people per room | 2917 | 1428 (49.0) |
|
| ||
| Pregnancy characteristics | ||
|
| ||
| Gestational age at enrollment (weeks) | 2949 | 24 (20, 28) |
|
| ||
| Previous pregnancy | 2934 | 2261 (77.1) |
|
| ||
| Previous abortion/miscarriage | 2930 | 314 (10.7) |
|
| ||
| Previous premature birth (<37 weeks) | 2949 | 30 (1.0) |
|
| ||
| Behavioral characteristics | ||
|
| ||
| No. of lifetime sexual partners | 2939 | 2 (2, 3) |
|
| ||
| HIV status of primary sexual partner(s) | 2942 | |
| Positive | 126 (4.3) | |
| Negative | 1880 (63.9) | |
| Unknown | 902 (30.7) | |
| No male partner | 34 (1.2) | |
|
| ||
| Partner on ART if HIV-positive | 121 | 116 (95.9) |
|
| ||
| Syphilis Positive (RPR, HIV/Syphilis dual) | 2895 | 29 (1.0) |
|
| ||
| In the last 6 months: | ||
| Exchange sex for money or favors | 2937 | 51 (1.7) |
| Diagnosed or treated for an STI | 2937 | 70 (2.4) |
| Forced to have sex against will | 2936 | 145 (4.9) |
| Experience intimate partner violence 1 | 2932 | 230 (7.8) |
| Shared needles during drug use | 2936 | 7 (0.2) |
| Used PEP >2 times | 2934 | 8 (0.3) |
|
| ||
| High HIV risk score 2 | 2949 | 1075 (36.5) |
|
| ||
| Psychosocial characteristics | ||
|
| ||
| Heard of PrEP before | 2922 | 1438 (49.2) |
|
| ||
| Know someone on PrEP | 2932 | 205 (7.0) |
|
| ||
| High perceived HIV risk 3 | 2928 | 250 (8.5) |
|
| ||
| High self-efficacy to take daily medication 4 | 2811 | 1966 (69.9) |
STI=sexually transmitted infection
HITS score ≥ 10
HIV risk score ≥6 (translating to HIV incidence 7.3 per 100 person-years) 31
Self-perceived HIV risk assessed by asking “What is your gut feeling about how likely you are to get infected with HIV?”, with possible responses of “extremely likely”, “very likely”, “somewhat likely”, “very unlikely”, “extremely unlikely”. (High self-perceived HIV risk: Extremely likely/Very likely = “Yes”, Somewhat likely/very unlikely/extremely unlikely = “No”).
Self-efficacy to take a daily oral medication assessed by asking participants to rank on a 0–10 scale (0=Cannot do it at all, 10=Completely certain can do it) their response to the question: “How confident are you that you can integrate a daily medication into your daily routine? (High self-efficacy to take daily medication: >=5)