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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Alzheimers Dement. 2023 Jun 6;19(9):4127–4138. doi: 10.1002/alz.13314

Figure 1. Age trajectories of plasma P-tau217 and NfL in male and female PSEN1 mutation carriers.

Figure 1.

(A) Log10 Plasma P-tau217 as a function of age. (B) LOESS plot of Log10 Plasma P-tau217 as a function of age. (C) Log10 Plasma NfL as a function of age. (D) LOESS plot of Log10 Plasma NfL as a function of age. Dashed line represents the age at which male and female carriers LOESS fit confidence band separate (age of 48.45). Abbreviations: NfL, Neurofilament light chain; P-tau217, Plasma-measured tau phosphorylated at threonine 217. Orange represents female carriers and green represents male carriers.