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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Alzheimers Dement. 2023 Jun 6;19(9):4127–4138. doi: 10.1002/alz.13314

Figure 2. Associations between plasma P-tau217 and NfL and cognitive performance in male and female PSEN1 mutation carriers.

Figure 2.

(A) CERAD word list delayed recall as a function of Log10 Plasma P-tau217. (B) API cognitive composite score as a function of Log10 Plasma P-tau217. (C) CERAD word list delayed recall as a function of Log10 Plasma NfL. (D) API cognitive composite score as a function of Log10 Plasma NfL. Abbreviations: NfL, Neurofilament light chain; P-tau217, Plasma-measured tau phosphorylated at threonine 217; CERAD, Consortium to Establish a Registry for Alzheimer’s Disease; API, Alzheimer Prevention Initiative. Orange represents female carriers, and green represents male carriers. Circles represent cognitively unimpaired carriers, and triangles represent cognitively impaired carriers.