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Obatoclax disrupts the BECN1-BCL2 complex in iPSC-derived neurons. Proximity ligation assay to assess the interaction of BECN1 and BCL2 in iPSC-derived neurons treated with DMSO and obatoclax at 10 nM for 24 h. The mean of eight independent experiments (n = 8); error bars indicate SEM. Treatments were analyzed via an unpaired Student’s t-test. * indicates p < 0.05. Scale bar = 10 μm.
