Table 4.

Standardized beta coefficient of linear regression of relationship between LA strain/ function estimates and different factors.

Variables		LAEF, %		LARS, %		LALAS, %
Variables		Univariate model	Multivariate model^a	Univariate model	Multivariate model^a	Univariate model	Multivariate model^a
Demographic factors	Age, years^b	−.30		−.37 ^*		−.30
	Sex ^b	−.07		−.08		−.05
	Race^b	−.16		−.23		−.33 ^*
Comorbidities and Anthropometric factors	CAD severity^b	−.50 ^**	−.39 ^**	−.37 ^*	−.41 ^**	−.39 ^*	−.33 ^*
	Hypertension^b	−.24		−.36 ^*		−.33 ^*
	Diabetes Mellitus^b	−.30		.03		−.07
	Body Mass Index, kg/m²	.01		.26		.10
Medications	AI/AT1RB	−.08		−.11		−.22
	Beta-blockers	−.21		−.11		−.26
	Diuretics	−.17		−.38 ^*	−.42 ^**	−.17
	Nitrates	−.48 ^**	−.37 ^**	−.41 ^*		−.48 ^*	−.43 ^**
	Calcium Blockers	.16		−.05		.22
	Insulin/Oral Hypoglycemics	−.23		.00		−.12
LA and LV volumes	LAV minimum Index, ml/m²	−.40 ^*	−.28 ^*	−.05		−.26
	LAV maximum Index, ml/m²	.09		.22		−.01
	LVEDVI, ml/m²	.28		.20		.10
	LVSVI, ml/m²	.31		.32		.20
LV function	LVEF, %	.05		.15		.19
	Heart Rate, bpm	−.11		−.14		.08
	Cardiac Index, ml/min/m²	.23		.22		.28
	LVEDP, mmHg	−.04		.12		.10

CAD=coronary artery disease; LAEF=left atrial emptying fraction; LARS=left atrial reservoir strain; LALAS=left atrial long-axis shortening; AI/AT1RB= angiotensin-converting enzyme inhibitor/ Angiotensin II type-1 receptor blocker; LAV=left atrial volume; LA=left atrial; LV=left ventricular; LVEDVI=left ventricular end diastolic volume index; LVSVI= left ventricular stroke volume index; LVEF= left ventricular ejection fraction; LVEDP=left ventricular end ventricular pressure.

P<0.05

^**

P<0.01

^***

P<0.005.

Backward multivariate linear regression model was built (probability of F for entry: 0.5 and removal: 0.1) by testing variables with P<0.05 in univariate model.

CAD severity, (1 no, 2 mild-to-moderate, 3 severe) Sex, (1 M/2 F) Race, (1 AA/2 W), Medications (1 no, 2 yes), Hypertension (0 no, 1 yes), Diabetes Mellitus (0 no, 1 yes).