Table 2.
In vivo mean ADC values and repeatability/reproducibility wCV for each DWI sequence. Volume and mean ADC values are represented as mean ± standard deviation. wCV values are represented as wCV (upper and lower 95% confidence interval) and expressed as a percentage. Sequences are color-coded to group sequences with similar acquisition mechanisms that can be directly compared.
| EPIMR-linac | SPLICE | TSE | EPIMR sim | BLADE | RESOLVE | ||
|---|---|---|---|---|---|---|---|
| Sequence Description | Single-shot SE EPI | Single-shot TSE with split acquisition of spin echo and stimulated echo | Single-shot TSE | Single-shot SE EPI | Multi-shot radial TGSE | Multi-shot SE EPI | |
| Parotid Glands Volume (cm3): 32.9 ± 16.0 | Mean ADC (×10−3 mm2/s) | 1.14 ± 0.17 | 1.20 ± 0.23 | 0.93 ± 0.18 | 1.49 ± 0.20 | 1.14 ± 0.15 | 1.19 ± 0.16 |
| Repeatability wCV (%) | 5.41 (4.42 – 6.97) | 3.83 (3.13 – 4.94) | 5.66 (4.63 – 7.29) | 3.44 (2.81 – 4.43) | 5.04 (4.12 – 6.50) | 4.23 (3.46 – 5.45) | |
| Reproducibility wCV (%) | 6.72 (5.49 – 8.66) | 8.80 (7.19 – 11.34) | 10.03 (8.20 – 12.92) | 5.70 (4.64 – 7.40) | 5.66 (4.62 – 7.29) | 7.36 (5.99 – 9.56) | |
| Primary Tumors Volume (cm3): 10.7 ± 10.4 | Mean ADC (×10−3 mm2/s) | 1.33 ± 0.22 | 1.80 ± 0.19 | 1.36 ± 0.19 | |||
| Repeatability wCV (%) | 9.64 (7.23 – 14.45) | 7.84 (5.84 – 11.93) | 7.60 (5.70 – 11.40) | ||||
| Reproducibility wCV (%) | 10.28 (7.65 –15.64) | 8.96 (6.56 – 14.14) | 11.68 (8.70 – 17.78) | ||||
| Lymph Nodes Volume (cm3): 7.3 ± 8.0 | Mean ADC (×10−3 mm2/s) | 1.38 ± 0.40 | 1.53 ± 0.36 | 1.31 ± 0.42 | |||
| Repeatability wCV (%) | 7.80 (6.59 – 9.55) | 7.23 (6.06 – 8.96) | 10.82 (9.15 – 13.25) | ||||
| Reproducibility wCV (%) | 9.95 (8.37 – 12.25) | 8.48 (7.00 – 10.78) | 10.44 (8.79 – 12.86) |