Legend: Area under receiver operating characteristic (AUROC), sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for each model. Models listed are: Random Forests (RF), Decision Trees (DT), Boosted Trees (BT), and Neural Networks (NN). Models listed including pre-viability variables, all-pregnancy variables, Exploratory Factor Analysis (EFA)-derived variables, and pre-viability variables without 2nd trimester serum screening. Asterisk (*) indicates best model for the given set of variables.